Searchable abstracts of presentations at key conferences in endocrinology

Endocrine Abstracts

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ea0035p661 | Female reproduction | ECE2014

Mood disturbances in women with polycystic ovary syndrome

Zabuliene Lina , Navickaite Aurelija , Urboniene Jurgita

Mood disturbances accompanying the symptoms and hormonal abnormalities are important, but underestimated, in polycystic ovary syndrome (PCOS). Our objective was to assess psychological features in women with and without PCOS.Materials and methods: We investigated 116 PCOS women (according to the Rotterdam criteria) and 81 healthy control women in Vilnius city (Lithuania) in 2009–2011. Levels of anxiety and depression were measured using the Hospital...
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ea0056p191 | Bone ' Osteoporosis | ECE2018

Tumor-induced osteomalacia associated with mesenchymal tumor: a challenging case report

Daneliene Milda , Krasauskiene Aurelija , Barsiene Lina , Lukosevicius Saulius , Zilaitiene Birute

Introduction: Tumor-induced osteomalacia (TIO) or oncogenic hypophosphatemic osteomalacia (OHO) is a rare paraneoplastic syndrome characterized by renal phosphate wasting leading to hypophosphatemia and secondary osteomalacia. TIO was first described in 1947 by Robert McCance and only 500 of cases have been reported in literature since then, approximately 200 of cases during this decade.Case report: In 2014, a 32-year-old female presented with waist pain...
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ea0073aep222 | Diabetes, Obesity, Metabolism and Nutrition | ECE2021

Insulin resistance in association with cardiovascular risk factors and thyroid function

Kazukauskiene Nijole , Podlipskyte Aurelija , Varoneckas Giedrius , Narseta Mickuviene

Insulin resistance (IR) occurs as part of a cluster of cardiovascular-metabolic abnormalities. Given the seriousness of the cardiovascular diseases data there is the increasing burden of diabetes.The aim of the study was to investigate insulin resistant in association with cardiovascular risk factors among 45–84-year-old citizens of Palanga.MethodsA randomized epidemiological study was performed with 850...
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ea0049gp244 | Thyroid Cancer & Thyroid Case Reports | ECE2017

Expressions of miRNAs and BRAFV600E mutation detection in papillary thyroid carcinoma

Simanaviciene Vaida , Kondrotiene Aiste , Pamedytyte Daina , Sarauskas Valdas , Dauksiene Dalia , Dauksa Albertas , Zvirbliene Aurelija , Zilaitiene Birute

Introduction: Papillary thyroid carcinoma (PTC) is the most common type of thyroid malignancy. For the majority of patients with PTC, the prognosis is very good; however, up to 20% of patients suffer disease recurrence. Currently, the risk stratification for PTC recurrence is based on clinicopathological features which have limited prognostic value. Identification of molecular biomarkers of PTC recurrence such as protooncogene BRAF and miRNAs may help to improve risk-stratifie...
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ea0056p1173 | Thyroid cancer | ECE2018

Relationship between microRNA expression levels and tumor size in patients with papillary thyroid carcinoma

Pamedytyte Daina , Simanaviciene Vaida , Zvirbliene Aurelija , Kazokaite Mintaute , Sarauskas Valdas , Dauksiene Dalia , Dauksa Arbertas , Zilaitiene Birute

Introduction: Despite low mortality rates of patients with papillary thyroid carcinoma (PTC), disease progression in PTC occurs in up to 20% of patients. Currently, recurrence risk stratification is accomplished by using clinicopathologic factors, despite their limited prognostic value. Some data suggest that patient age at disease onset and primary tumor size may predict the risk of disease progression. Identification of possible associations of traditional clinicopathologica...
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ea0081ep567 | Endocrine-Related Cancer | ECE2022

Association of tissue miRNA (MiR-146b, -21, -221, -222, -181b) expression and the overall survival of papillary thyroid carcinoma patients

Kondrotienė Aistė , Dauksa Albertas , Pamedytytė Diana , Kazokaitė Mintautė , Žvirblienė Aurelija , Daukšienė Dalia , Simanavičienė Vaida , Klimaitė Raimonda , Verkauskienė Rasa , Zilaitiene Birute

Introduction: Improper management of papillary thyroid carcinoma (PTC) patients results in potentially higher fatal outcomes due to a lack of relevant prognostic markers, inadequate periodic individualized risk assessments and/or insufficient initial treatment. MiR-146b, -21, -221, -222, -181b are potential biomarkers for risk stratification in PTC.Aim: The aim of our study was to analyze expression levels of five miRNA molecules (miR-21; miR -221; miR -...
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ea0070aep931 | Thyroid | ECE2020

Evaluation of miRNA-222, –146b, –181b as possible diagnostic markers in patients with papillary thyroid carcinoma

Kondrotiene Aiste , Pamedytyte Daina , Simanaviciene Vaida , Dauksiene Dalia , Zvirbliene Aurelija , Kazokaite Mintaute , Klimaite Raimonda , Sarauskas Valdas , Daukša Albertas , Verkauskiene Rasa , Zilaitiene Birute

Introduction: The sensitivity and specificity of biomarkers which have been used in clinical practice for diagnosis of papillary thyroid carcinoma (PTC) are low. It is essential to develop novel diagnostic biomarkers for PTC.Objective: We aimed to explore the expression levels of miR-222, – 146b, –181b in PTC tissue and plasma samples and to compare with benign thyroid nodules (BTN).Methods: We collected plasma samples ...
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ea0090p234 | Thyroid | ECE2023

Lower expression of miR-21 is related to multifocal lesions of papillary thyroid carcinoma

Kondrotienė Aistė , Daukša Albertas , Pamedytyte Diana , Kazlauskienė Mintautė , Žvirblienė Aurelija , Daukšienė Dalia , Simanavičienė Vaida , Klimaitė Raimonda , Šarauskas Valdas , Verkauskienė Rasa , Žilaitienė Birutė

Introduction: Multifocality empirically is often treated as a risk factor for aggressive course of papillary thyroid carcinoma (PTC), encouraging aggressive treatments. However, inconsistency and even contradiction in a literature is present concerning the role of tumor multifocality in clinical outcomes of PTC. Therefore, the prognostic value of multifocality of PTC remains controversial, creating a difficulty in the current clinical management.Methods....
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ea0073aep387 | Endocrine-Related Cancer | ECE2021

MiR-146b, -21, -221, -222, -181b expression is related to clinicopathologic features of PTC

Aistė Kondrotienė , Dauksa Albertas , Daina Pamedytytė , Mintautė Kazokaitė , Aurelija Žvirblienė , Dalia Daukšienė , Vaida Simanavičienė , Raimonda Klimaitė , Valdas Šarauskas , Rasa Verkauskienė , Birutė Žilaitienė

IntroductionInadequately managed papillary thyroid carcinoma (PTC) patients result in potentially higher fatal outcomes due to a lack of sufficient prognostic data/markers, inadequate periodic individualized follow-up risk assessments and/or insufficient initial treatment. MiR-146b, -21, -221, -222, -181b are potential biomarkers for risk stratification of PTC.AimThe aim of our study was to analyze expression...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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